Article
Non-invasive fetal RHD and RHCE genotyping using real-time PCR testing of maternal plasma in RhD-negative pregnancies.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Mar 2005
Hromadnikova Ilona, Vechetova Lenka, Vesela Klara, Benesova Blanka, Doucha Jindrich, Vlk Radovan
Abstract excerpt
We assessed the feasibility of fetal RHD and RHCE genotyping by analysis of DNA extracted from plasma samples of RhD-negative pregnant women using real-time PCR and primers and probes targeted toward RHD and RHCE genes. We analyzed 45 pregnant women in the 11th to 40th weeks of pregnancy and correlated the results with serological analysis of cord blood after delivery. Non-invasive prenatal fetal RHD exon 7, RHD...
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