Article
Non-invasive fetal RHD genotyping in the first trimester of pregnancy.
Clinical chemistry and laboratory medicine - 1 Aug 2010
Cardo Leyre, García Belén Prieto, Alvarez Francisco V
Abstract excerpt
BACKGROUND: Hemolytic disease of the fetus and newborn (HDN) is caused primarily by feto-maternal RhD incompatibility. Although all RhD negative pregnant women undergo routine antenatal RhD prophylaxis at 28 weeks of gestation, and following delivery if the newborn is RhD positive, HDN has not been eradicated. Here, we investigated fetal Rhesus D (RHD) genotype in maternal plasma during the first trimester of...
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