Article
Non-invasive foetal RHD genotyping via real-time PCR of foetal DNA from Chinese RhD-negative maternal plasma.
European journal of clinical investigation - 1 Jul 2009
Wang X D, Wang B L, Ye S L, Liao Y Q, Wang L F, He Z M
Abstract excerpt
BACKGROUND: A majority of studies predicting the foetal RhD blood group in free foetal DNA from RhD-negative maternal plasma have been conducted in Caucasian populations, whereas limited data have been accumulated for Asian populations. In this study, we assessed the feasibility of prenatal genotyping of RHD in RhD-negative Chinese pregnant women. MATERIALS AND METHODS: Cell-free plasma DNA was extracted from 78...
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