Article
Large-scale pre-diagnosis study of fetal RHD genotyping by PCR on plasma DNA from RhD-negative pregnant women.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology - 1 Jan 2004
Rouillac-Le Sciellour Christelle, Puillandre Philippe, Gillot Rolande, Baulard Céline, Métral Sylvain, Le Van Kim Caroline, Cartron Jean-Pierre, Colin Yves, Brossard Yves
Abstract excerpt
BACKGROUND: The routine prenatal determination of fetal RhD blood group would be very useful in the management of pregnancies in RhD-negative women, as up to 40% of these pregnancies bear a RhD-negative fetus. The fetal DNA present in maternal plasma offers an opportunity for risk-free prenatal diagnosis. AIM: This study focused on the feasibility and accuracy of large-scale RhD fetal diagnosis in non-immunized...
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