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Investigation of discrepancies obtained during 15 years of non-invasive fetal RHD genotyping in apparent serologic RhD-negative pregnant women.

Prenatal diagnosis - 1 Sept 2022

Dufour Patrice, Gerard Christiane, Chantraine Frédéric, Minon Jean-Marc

Abstract excerpt

OBJECTIVES: In some European countries, non-invasive fetal RHD genotyping is the first step of anti-D allo-immunized pregnant women management but presence of RHD variant alleles may interfere with the results accuracy. We developed an algorithm allowing solving discordant results (due to the presence of RHD variant) in fetal RHD genotyping assay. METHOD: This study gathered the results of fetal RHD genotyping...

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PMID: 35933700
DOI: 10.1002/pd.6219

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