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Article

Phosphorylation-dependent binding of 14-3-3 to Par3beta, a human Par3-related cell polarity protein.

Biochemical and biophysical research communications - 1 Apr 2005

Izaki Tomoko, Kamakura Sachiko, Kohjima Motoyuki, Sumimoto Hideki

Abstract excerpt

Mammalian Par3alpha and Par3beta/Par3L participate in cell polarity establishment and localize to tight junctions of epithelial cells; Par3alpha acts via binding to atypical PKC (aPKC). Here we show that Par3beta as well as Par3alpha interacts with 14-3-3 proteins in a phosphorylation-dependent manner. In the interaction, Ser-746 of Par3beta and the corresponding residue of Par3alpha (Ser-814) likely play a...

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PMID: 15721295
DOI: 10.1016/j.bbrc.2005.01.115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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