Article

Par3A and Par3B orchestrate podocyte architecture by regulating RhoA levels

2020-02-10

Abstract excerpt

Glomerular diseases are a major cause for chronic kidney disorders. In the majority of cases podocyte injury is causative for disease development. Cytoskeletal rearrangements and morphological changes are hallmark features of podocyte injury and result in dedifferentiation and subsequent loss of podocytes. Here, we establish a link between components of the Par3 polarity complex and actin regulators, which are nec...

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Literature Corpus work: ad670982-dc8d-57ff-a246-cd3168f76ce4
DOI: 10.1101/2020.02.10.933671

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