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Article

Inherited and acquired interactions between ACHE and PON1 polymorphisms modulate plasma acetylcholinesterase and paraoxonase activities.

Journal of neurochemistry - 1 Mar 2005

Bryk Boris, BenMoyal-Segal Liat, Podoly Erez, Livnah Oded, Eisenkraft Arik, Luria Shai, Cohen Amir, Yehezkelli Yoav, Hourvitz Ariel, Soreq Hermona

Abstract excerpt

The 5.5 Mb chromosome 7q21-22 ACHE/PON1 locus harbours the ACHE gene encoding the acetylcholine hydrolyzing, organophosphate (OP)-inhibitable acetylcholinesterase protein and the paraoxonase gene PON1, yielding the OP-hydrolyzing PON1 enzyme which also displays arylesterase activity. In search of inherited and acquired ACHE-PON1 interactions we genotyped seven polymorphic sites and determined the hydrolytic...

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Source

Identifiers

PMID: 15715671
DOI: 10.1111/j.1471-4159.2004.02959.x

Genes

PON1
ACHE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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