Article
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study.
Proceedings of the National Academy of Sciences of the United States of America - 13 Apr 2004
Sklan Ella H, Lowenthal Alexander, Korner Mira, Ritov Ya'acov, Landers Daniel M, Rankinen Tuomo, Bouchard Claude, Leon Arthur S, Rice Treva, Rao D C, Wilmore Jack H, Skinner James S, Soreq Hermona
Abstract excerpt
Anxiety involves complex, incompletely understood interactions of genomic, environmental, and experience-derived factors, and is currently being measured by psychological criteria. Here, we report previously nonperceived interrelationships between expression variations and nucleotide polymorphisms of the chromosome 7q21-22 acetylcholinesterase-paraoxonase 1 (ACHE-PON1) locus with the trait- and state-anxiety...
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