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Article

Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2006

Browne R Orie, Moyal-Segal Liat Ben, Zumsteg Dominik, David Yaron, Kofman Ora, Berger Andrea, Soreq Hermona, Friedman Alon

Abstract excerpt

Organophosphate pesticides (OPs), known inhibitors of acetylcholinesterase (AChE), are used extensively throughout the world. Recent studies have focused on the ACHE/PON1 locus as a determinant of inherited susceptibility to environmental OP exposure. To explore the relationship of the corresponding gene-environment interactions with brain activity, we integrated neurophysiologic, neuropsychological, biochemical,...

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Source

Identifiers

PMID: 16807370
DOI: 10.1096/fj.05-5576fje

Genes

ACHE
PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure.PMID 16807370Read ↗

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