Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacogenetics of paraoxonases: a brief review.

Naunyn-Schmiedeberg's archives of pharmacology - 1 Jan 2004

Draganov D I, La Du B N

Abstract excerpt

The human paraoxonase (PON) gene family consists of three members, PON1, PON2, and PON3, aligned next to each other on chromosome 7. By far the most-studied member of the family is the serum paraoxonase 1 (PON1), a high-density lipoprotein-associated esterase/lactonase. Early research focused on its capability to hydrolyze toxic organophosphates, and its name derives from one of its most commonly used in vitro...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryldialkylphosphatase
Share to Cardiovascular Diseases
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inactivation, Metabolic

Share to Pharmacogenetics

Share to Polymorphism, Genetic

Share to Substrate Specificity

Share to Xenobiotics

Source

Identifiers

PMID: 14579013
DOI: 10.1007/s00210-003-0833-1

Genes

PON1
PON2
PON3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacogenetics of paraoxonases: a brief review.PMID 14579013Read ↗

Paraoxonase (PON1): from toxicology to cardiovascular medicine.Semantic proximity Read ↗

Pharmacological Interactions of Paraoxonase 1 (PON1): A HDL-Bound Antiatherogenic Enzyme.Semantic proximity Read ↗

Paraoxonases-1, -2 and -3: What are their functions?Semantic proximity Read ↗

Paraoxonase (PON)-1: a brief overview on genetics, structure, polymorphisms and clinical relevance.Semantic proximity Read ↗

Paraoxonase genes and disease.Semantic proximity Read ↗

Biochemical, environmental, and genetic factors associated with paraoxonase (PON1) activity.Semantic proximity Read ↗

The paraoxonase 1, 2 and 3 in humans.Semantic proximity Read ↗

Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism.Semantic proximity Read ↗

Paraoxonase (PON1) polymorphism and activity as the determinants of sensitivity to organophosphates in human subjects.Semantic proximity Read ↗

Paraoxonase gene polymorphisms, oxidative stress, and diseases.Semantic proximity Read ↗

Modulation of paraoxonases during infectious diseases and its potential impact on atherosclerosisSemantic proximity Read ↗

Paraoxonase-1 (PON1) Status Analysis Using Non-Organophosphate Substrates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.