Article
Conserved cross-interactions in Drosophila and Xenopus between Ras/MAPK signaling and the dual-specificity phosphatase MKP3.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2005
Gómez Ana Ruiz, López-Varea Ana, Molnar Cristina, de la Calle-Mustienes Elisa, Ruiz-Gómez Mar, Gómez-Skarmeta José Luis, de Celis Jose F
Abstract excerpt
The extracellular signal-regulated kinase (ERK) is a key transducer of the epidermal growth factor receptor (EGFR) and fibroblast growth factor receptor (FGFR) signaling pathways, and its function is required in multiple processes during animal development. The activity of ERK depends on the phosphorylation state of conserved threonine and tyrosine residues, and this state is regulated by different kinases and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
