Article
MKP-3 has essential roles as a negative regulator of the Ras/mitogen-activated protein kinase pathway during Drosophila development.
Molecular and cellular biology - 1 Jan 2004
Kim Myungjin, Cha Guang-Ho, Kim Sunhong, Lee Jun Hee, Park Jeehye, Koh Hyongjong, Choi Kang-Yell, Chung Jongkyeong
Abstract excerpt
Mitogen-activated protein kinase (MAPK) phosphatase 3 (MKP-3) is a well-known negative regulator in the Ras/extracellular signal-regulated kinase (ERK)-MAPK signaling pathway responsible for cell fate determination and proliferation during development. However, the physiological roles of MKP-3 an...
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