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Article

Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation.

American journal of human genetics - 1 Mar 2005

Stephens Matthew, Scheet Paul

Abstract excerpt

Although many algorithms exist for estimating haplotypes from genotype data, none of them take full account of both the decay of linkage disequilibrium (LD) with distance and the order and spacing of genotyped markers. Here, we describe an algorithm that does take these factors into account, using a flexible model for the decay of LD with distance that can handle both "blocklike" and "nonblocklike" patterns of...

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Identifiers

PMID: 15700229
DOI: 10.1086/428594
PMCID: PMC1196397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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