Article
A combined long-range phasing and long haplotype imputation method to impute phase for SNP genotypes.
Genetics, selection, evolution : GSE - 10 Mar 2011
Hickey John M, Kinghorn Brian P, Tier Bruce, Wilson James F, Dunstan Neil, van der Werf Julius H J
Abstract excerpt
BACKGROUND: Knowing the phase of marker genotype data can be useful in genome-wide association studies, because it makes it possible to use analysis frameworks that account for identity by descent or parent of origin of alleles and it can lead to a large increase in data quantities via genotype or sequence imputation. Long-range phasing and haplotype library imputation constitute a fast and accurate method to...
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