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Article

The use of family relationships and linkage disequilibrium to impute phase and missing genotypes in up to whole-genome sequence density genotypic data.

Genetics - 1 Aug 2010

Meuwissen Theo, Goddard Mike

Abstract excerpt

A novel method, called linkage disequilibrium multilocus iterative peeling (LDMIP), for the imputation of phase and missing genotypes is developed. LDMIP performs an iterative peeling step for every locus, which accounts for the family data, and uses a forward-backward algorithm to accumulate information across loci. Marker similarity between haplotype pairs is used to impute possible missing genotypes and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20479147
DOI: 10.1534/genetics.110.113936
PMCID: PMC2927768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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