Article
Methods to impute missing genotypes for population data.
Human genetics - 1 Dec 2007
Yu Zhaoxia, Schaid Daniel J
Abstract excerpt
For large-scale genotyping studies, it is common for most subjects to have some missing genetic markers, even if the missing rate per marker is low. This compromises association analyses, with varying numbers of subjects contributing to analyses when performing single-marker or multi-marker analyses. In this paper, we consider eight methods to infer missing genotypes, including two haplotype reconstruction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
