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Article

Mutations of beta-catenin and AXIN I genes are a late event in human hepatocellular carcinogenesis.

Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2005

Park Jik Young, Park Won Sang, Nam Suk Woo, Kim Su Young, Lee Sug Hyung, Yoo Nam Jin, Lee Jung Young, Park Cheol Keun

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is a well-known cancer involving the Wnt pathway in its carcinogenesis. AIMS: However, it is not clear whether these genetic changes are early genetic events in hepatocarcinogenesis or not. METHOD: In this study, we performed mutational analysis of the beta-catenin and AXIN I genes, and immunohistochemistry for beta-catenin in a series of 114 hepatocellular nodular...

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Identifiers

PMID: 15698401
DOI: 10.1111/j.1478-3231.2004.0995.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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