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Article

Specific features of ß-catenin-mutated hepatocellular carcinomas.

British journal of cancer - 1 Dec 2024

Dantzer Camille, Dif Lydia, Vaché Justine, Basbous Sara, Billottet Clotilde, Moreau Violaine

Abstract excerpt

CTNNB1, encoding the ß-catenin protein, is a key oncogene contributing to liver carcinogenesis. Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer in adult, representing the third leading cause of cancer-related death. Aberrant activation of the Wnt/ß-catenin pathway, mainly due to mutations of the CTNNB1 gene, is observed in a significant subset of HCC. In this review, we first resume...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39261716
DOI: 10.1038/s41416-024-02849-7
PMCID: PMC11628615

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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