Exploring the Impact of the β-Catenin Mutations in Hepatocellular Carcinoma: An In-Depth Review.

doi:10.1177/10732748241293680

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Article

Exploring the Impact of the β-Catenin Mutations in Hepatocellular Carcinoma: An In-Depth Review.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2024

Idrissi Yassine Alami, Rajabi Mohammad Reza, Beumer Jan H, Monga Satdarshan P, Saeed Anwaar

Abstract excerpt

Liver cancer, primarily hepatocellular carcinoma, represents a major global health issue with significant clinical, economic, and psychological impacts. Its incidence continues to rise, driven by risk factors such as hepatitis B and C infections, nonalcoholic steatohepatitis, and various environmental influences. The Wnt/β-Catenin signaling pathway, frequently dysregulated in HCC, emerges as a promising...

Topics

Humans
beta Catenin
Carcinoma, Hepatocellular
Liver Neoplasms
Mutation
Wnt Signaling Pathway
Animals

Source

Open in PubMed Open full text

Identifiers

PMID: 39428608
DOI: 10.1177/10732748241293680
PMCID: PMC11528747

Genes

CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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