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Article

Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas.

International journal of oncology - 1 May 2004

Ishizaki Yasuyo, Ikeda Satoshi, Fujimori Masahiko, Shimizu Yosuke, Kurihara Takeshi, Itamoto Toshiyuki, Kikuchi Akira, Okajima Masazumi, Asahara Toshimasa

Abstract excerpt

Several lines of evidence show that the development of hepatocellular carcinoma (HCC) requires an accumulation of genetic alterations. However, molecular mechanism in HCC carcinogenesis remains unsolved. A total of 89 HCC samples were analyzed in this study to determine how alterations in the Wnt...

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PMID: 15067328

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15067328-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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