Article
Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Feb 2005
Carroll W D, Lenney W, Child F, Strange R C, Jones P W, Fryer A A
Abstract excerpt
Maternal factors are known to influence the heritability and expression of asthma and atopy. We report the association of maternal, paternal and proband GSTP1 genotype with lung function in 145 Caucasian children with asthma. GSTP1 Val105/Val105 and Ala114/Val114 genotypes in the child were associated with non-significant increases in lung function (forced expiratory volume in 1 second (FEV1), forced vital...
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