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Article

Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children.

American journal of respiratory and critical care medicine - 15 Aug 2002

Gilliland Frank D, Li Yu-Fen, Dubeau Louis, Berhane Kiros, Avol Edward, McConnell Rob, Gauderman W James, Peters John M

Abstract excerpt

The rise in childhood asthma prevalence suggests a role for environmental factors in the etiology of this evolving epidemic; however, genetics also influence the occurrence of asthma. Glutathione S-transferase (GST) M1 may play a role in asthma and wheezing occurrence among those exposed to tobacco smoke, as it functions in pathways involved in asthma pathogenesis such as xenobiotic metabolism and antioxidant...

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Source

Identifiers

PMID: 12186820
DOI: 10.1164/rccm.2112064

Genes

GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children.PMID 12186820Read ↗

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Associations of glutathione S-transferase P1, M1, and environmental tobacco smoke with wheezing illness in school children.Semantic proximity Read ↗

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In utero smoke exposure and role of maternal and infant glutathione s-transferase genes on airway responsiveness and lung function in infancy.Semantic proximity Read ↗

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Glutathione S transferase deficiency and passive smoking increase childhood asthma.Semantic proximity Read ↗

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