Article
Glutathione S-transferase M1 and P1 genotype, passive smoking, and peak expiratory flow in asthma.
Pediatrics - 1 Aug 2006
Palmer Colin N A, Doney Alex S F, Lee Simon P, Murrie Inez, Ismail Tahmina, Macgregor Donald F, Mukhopadhyay Somnath
Abstract excerpt
OBJECTIVES: Our purpose with this work was to assess the contribution of glutathione S-transferase gene variants to asthma susceptibility and pulmonary function in relation to tobacco smoke exposure in the home. METHODS: Young individuals with asthma (age: 3-21 years; n = 504) were recruited through primary and secondary care throughout Tayside, Scotland (BREATHE Study). Spirometry was obtained on 407...
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