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Article

Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis.

Environmental health perspectives - 1 Mar 2008

Li Yu-Fen, Gauderman W James, Conti David V, Lin Pi-Chu, Avol Edward, Gilliland Frank D

Abstract excerpt

BACKGROUND: Glutathione S-transferase P1 (GSTP1) plays a role in a spectrum of respiratory diseases; however, the effects of sequence variation across the entire locus in asthma pathogenesis have yet to be determined. OBJECTIVES: This study was designed to investigate whether sequence variations in the GSTP1 coding and promoter regions are associated with asthma and wheezing outcomes and to determine whether...

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Source

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Identifiers

PMID: 18335111
DOI: 10.1289/ehp.10655
PMCID: PMC2265034

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis.PMID 18335111Read ↗

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The GSTP1 gene is a susceptibility gene for childhood asthma and the GSTM1 gene is a modifier of the GSTP1 gene.Semantic proximity Read ↗

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