Article
Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Sept 2005
Carroll W D, Lenney W, Jones P W, Strange R C, Child F, Whyte M K, Primhak R A, Fryer A A
Abstract excerpt
RATIONALE: Previous data have suggested that glutathione-S-transferase (GST) genotypes are important in determining the rate of lung function growth in childhood. This effect was most marked in Caucasian children with asthma. OBJECTIVES: We investigated the association of lung function with GSTM1, GSTP1 and GSTT1 genotypes in Caucasian families with asthma. METHODS: Four hundred and eighteen children and 316...
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