Article
Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia.
Molecular and cellular neurosciences - 1 Feb 2005
Lecomte Marie-José, De Gois Stéphanie, Guerci Aline, Ravassard Philippe, Faucon Biguet Nicole, Mallet Jacques, Berrard Sylvie
Abstract excerpt
Previous studies revealed that leukemia inhibitory factor (LIF) and retinoic acid (RA) induce a noradrenergic to cholinergic switch in cultured sympathetic neurons of superior cervical ganglia (SCG) by up-regulating the coordinate expression of choline acetyltransferase (ChAT) and the vesicular acetylcholine transporter. Here, we examined the effect of both factors on high-affinity choline uptake (HACU) and on...
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