Article
Recombinant cholinergic differentiation factor (leukemia inhibitory factor) regulates sympathetic neuron phenotype by alterations in the size and amounts of neuropeptide mRNAs.
Journal of neurochemistry - 1 Jun 1991
Nawa H, Nakanishi S, Patterson P H
Abstract excerpt
The cholinergic differentiation factor (CDF) in heart cells is identical to leukemia inhibitory factor (LIF). Recombinant CDF/LIF was shown to alter dramatically neurotransmitter production as well as the levels of several neuropeptides in cultured rat sympathetic neurons. Here it is shown that t...
Topics
- Animals
- Growth Inhibitors
- Interleukin-6
- Leukemia Inhibitory Factor
- Lymphokines
- Neurons
- Neuropeptides
- Phenotype
- RNA, Messenger
- Recombinant Proteins
- Sympathetic Nervous System