Regulation of expression of cholinergic neuronal phenotypic markers in neuroblastoma LA-N-2.

doi:10.1111/j.1471-4159.1993.tb13632.x

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Article

Regulation of expression of cholinergic neuronal phenotypic markers in neuroblastoma LA-N-2.

Journal of neurochemistry - 1 Oct 1993

Rylett R J, Goddard S, Lambros A

Abstract excerpt

Cholinergic neurons in PNS and CNS are identified by the presence of choline acetyltransferase and the accumulation of choline by a high-affinity, sodium-coupled choline transporter to be used for acetylcholine synthesis. It appears that expression of choline acetyltransferase can be altered by s...

Topics

Acetylcholine
Biological Transport
Biomarkers
Carrier Proteins
Cell Differentiation
Choline
DNA-Directed RNA Polymerases
Humans
Nerve Tissue Proteins
Neuroblastoma
Neurons
Parasympathetic Nervous System
Phenotype
Tumor Cells, Cultured

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