Induction of a serotonergic and neuronal phenotype in thyroid C-cells.

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Article

Induction of a serotonergic and neuronal phenotype in thyroid C-cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 1995

Clark M S, Lanigan T M, Page N M, Russo A F

Abstract excerpt

We have investigated whether rat thyroid C-cells can acquire a phenotype similar to serotonergic neurons. C-cells are neural crest derived endocrine cells with some intrinsic neuronal and serotonergic properties. A relatively simple isolation scheme yielded cultures of about 50% initial purity, as measured by fluorescence activated cell sorting. These enriched C-cells could extend neurites up to 550 microns on a...

Topics

Animals
Antigens, Surface
Base Sequence
Basic Helix-Loop-Helix Transcription Factors
Carrier Proteins
DNA-Binding Proteins
Female
Male
Membrane Glycoproteins
Membrane Transport Proteins
Molecular Probes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nerve Growth Factors

Nerve Tissue Proteins

Neurites

Neurofilament Proteins

Neurons

Phenotype

Source

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Identifiers

PMID: 7666199
PMCID: PMC6577694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7666199-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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