Article
Induction of a serotonergic and neuronal phenotype in thyroid C-cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 1995
Clark M S, Lanigan T M, Page N M, Russo A F
Abstract excerpt
We have investigated whether rat thyroid C-cells can acquire a phenotype similar to serotonergic neurons. C-cells are neural crest derived endocrine cells with some intrinsic neuronal and serotonergic properties. A relatively simple isolation scheme yielded cultures of about 50% initial purity, as measured by fluorescence activated cell sorting. These enriched C-cells could extend neurites up to 550 microns on a...
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