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Article

Cell Type-specific Regulation of Choline Acetyltransferase Gene Expression

1 Dec 1996

Abstract excerpt

This study demonstrates the presence of positive and negative regulatory elements within a 2336-base pair-long region of the rat choline acetyltransferase (ChAT) gene promoter that cooperate to direct cell type-specific expression in cholinergic cells. A 21-base pair-long neuron-restrictive silencer element (NRSE) was identified in the proximal part of this region. This element was recognized by the...

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PMID: 8969196
DOI: 10.1074/jbc.271.52.33358

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