Article
Stimuli that induce a cholinergic neuronal phenotype of NG108-15 cells upregulate ChAT and VAChT mRNAs but fail to increase VAChT protein.
Brain research bulletin - 1 Mar 2001
Dolezal V, Castell X, Tomasi M, Diebler M F
Abstract excerpt
The vesicular acetylcholine transporter (VAChT) and choline acetyltransferase (ChAT) are encoded by genes organized in a single gene locus, and coregulation of the transcription of the two genes has been repeatedly reported in cholinergic tissues. In the present study, different stimuli were used to induce the differentiation of the hybridoma cells NG108-15 and we examined their effects on the modulation of VAChT...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
