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Article

Functional implications of the noradrenergic-cholinergic switch induced by retinoic acid in NB69 neuroblastoma cells.

Journal of neuroscience research - 1 May 2000

Handler A, Lobo M D, Alonso F J, Paíno C L, Mena M A

Abstract excerpt

Some neuroblastoma cell lines change their neurotransmitter phenotype from noradrenergic to cholinergic under retinoic acid treatment. Such "neurotransmitter switch" seems to be a consequence of changes in the expression and activity of the biosynthetic machinery for both neurotransmitters. In this study, we have characterized this "neurotransmitter switch" induced by retinoic acid in a human neuroblastoma cell...

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Source

Identifiers

PMID: 10797533
DOI: 10.1002/(SICI)1097-4547(20000501)60:3<311::AID-JNR5>3.0.CO;2-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional implications of the noradrenergic-cholinergic switch induced by retinoic acid in NB69 neuroblastoma cells.PMID 10797533Read ↗

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