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Article

Persistence and loss of meiotic recombination hotspots.

Genetics - 1 Apr 2005

Pineda-Krch Mario, Redfield Rosemary J

Abstract excerpt

The contradiction between the long-term persistence of the chromosomal hotspots that initiate meiotic recombination and the self-destructive mechanism by which they act strongly suggests that our understanding of recombination is incomplete. This "hotspot paradox" has been reinforced by the finding that biased gene conversion also removes active hotspots from human sperm. To investigate the requirements for...

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Identifiers

PMID: 15687277
DOI: 10.1534/genetics.104.034363
PMCID: PMC1449581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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