Article
Sperm cross-over activity in regions of the human genome showing extreme breakdown of marker association.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jul 2008
Webb Adam J, Berg Ingrid L, Jeffreys Alec
Abstract excerpt
Population diversity data have recently provided profound, albeit inferential, insights into meiotic recombination across the human genome, revealing a landscape dominated by thousands of cross-over hotspots. However, very few of these putative hotspots have been directly analyzed for cross-over activity. We now describe a search for very active hotspots, by using extreme breakdown of marker association as a...
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