Article
Effect of IL-6 promoter polymorphism on incidence and outcome in Hodgkin's lymphoma.
British journal of haematology - 1 Feb 2005
Cordano Pablo, Lake Annette, Shield Lesley, Taylor G M, Alexander Freda E, Taylor Penelope R A, White Jo, Jarrett Ruth F
Abstract excerpt
A single nucleotide polymorphism (SNP) is present at position -174 of the human interleukin-6 gene. The risk of developing Hodgkin's lymphoma (HL) in young adults decreases with an increasing number of C alleles at this position. We analysed the effect of this SNP on incidence and outcome in HL. DNA samples from 408 cases and 349 controls were screened and analysed following stratification by age, histological...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
