Article
Interleukin-6 polymorphisms and hematologic malignancy: a re-appraisal of evidence from genetic association studies.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Nov 2013
Ziakas Panayiotis D, Karsaliakos Petros, Prodromou Michael L, Mylonakis Eleftherios
Abstract excerpt
CONTEXT: Interleukin-6 (IL-6) is implicated in the pathophysiology of hematologic neoplasia. OBJECTIVE: To review the role of IL-6 single nucleotide polymorphisms (SNPs) in hematologic neoplasia. METHODS: PubMed and EMBASE search of genetic association studies. Effects were summarized using the model-free generalized odds ratio (ORG), and the mode of inheritance was estimated for significant associations....
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