Article
Molecular screening of interleukin-6 gene promoter and influence of -174G/C polymorphism on breast cancer.
Cytokine - 1 Sept 2009
Chérel Michel, Campion Loïc, Bézieau Stéphane, Campone Mario, Charrier Josiane, Gaschet Joëlle, Ricolleau Gabriel, Gouraud Wilfried, Charbonnel Catherine, Jézéquel Pascal
Abstract excerpt
Interleukin-6 (IL-6) is a cytokine involved in different physiologic and pathophysiologic processes including carcinogenesis. In 2003, a single nucleotide polymorphism (-174G/C) of the IL-6 gene promoter has been linked to breast cancer prognosis in node-positive (N+) breast cancer patients. Sinc...
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