Article
Common genetic variants in candidate genes and risk of familial lymphoid malignancies.
British journal of haematology - 1 Aug 2009
Liang Xueying Sharon, Caporaso Neil, McMaster Mary Lou, Ng David, Landgren Ola, Yeager Meredith, Chanock Stephen, Goldin Lynn R
Abstract excerpt
Familial aggregation, linkage and case-control studies support the role of germline genes in the aetiology of lymphoid malignancies. To further examine the role of genetic variation underlying susceptibility, we analysed 1536 single nucleotide polymorphisms in 152 genes involved in apoptosis, DNA repair, immune response and oxidative stress pathways among a unique sample of 165 unrelated familial cases including...
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