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Article

Impact of interleukin-6 -174 G>C gene promoter polymorphism on neuroblastoma.

PloS one - 1 Jan 2013

Totaro Francesca, Cimmino Flora, Pignataro Piero, Acierno Giovanni, De Mariano Marilena, Longo Luca, Tonini Gian Paolo, Iolascon Achille, Capasso Mario

Abstract excerpt

BACKGROUND: Common variants in DNA may predispose to onset and progression of neuroblastoma (NB). The genotype GG of single nucleotide polymorphism (SNP) rs1800795 (-174 G>C) in interleukin (IL)-6 promoter has been associated with lower survival of high-risk NB. RESULT: To evaluate the impact of IL-6 SNP rs1800795 on disease risk and phenotype, we analyzed 326 Italian NB patients and 511 controls. Moreover, we...

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Source

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Identifiers

PMID: 24204677
DOI: 10.1371/journal.pone.0076810
PMCID: PMC3804531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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