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Article

Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor).

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2009

Lagmay Joanne P, London Wendy B, Gross Thomas G, Termuhlen Amanda, Sullivan Nicholas, Axel Amy, Mundy Bethany, Ranalli Mark, Canner Jason, McGrady Patrick, Hall Brett

Abstract excerpt

PURPOSE: Neuroblastoma is a childhood cancer of the sympathetic nervous system and many patients present with high-risk disease. Risk stratification, based on pathology and tumor-derived biomarkers, has improved prediction of clinical outcomes, but overall survival (OS) rates remain unfavorable and new therapeutic targets are needed. Some studies suggest a link between interleukin (IL)-6 and more aggressive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19671870
DOI: 10.1158/1078-0432.CCR-08-2953
PMCID: PMC2740837

Genes

EFS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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