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Article

Screening of 12 SNPs of CYP3A4 in a Chinese population using oligonucleotide microarray.

Genetic testing - 1 Jan 2004

Wen Siyuan, Wang Hong, Ding Yu, Liang Hao, Wang Shengqi

Abstract excerpt

Human cytochrome P450 3A4 (CYP34A) plays an important role in the metabolism of many endo- and xenomaterials. It also exhibits a substantial interindividual variation in enzymatic activity. It has been shown that the mutant alleles of CYP3A4 encoding inactive/decreased enzymes are largely caused by single nucleotide polymorphisms (SNPs) in the gene sequence. In the present study, with the goal of detecting the...

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Identifiers

PMID: 15684873
DOI: 10.1089/gte.2004.8.411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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