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Article

Novel HLA-DR2-related haplotypes in Hong Kong Chinese implicate the DQB1*0602 allele in susceptibility to multiple sclerosis.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jan 2000

Serjeantson S W, Gao X, Hawkins B R, Higgins D A, Yu Y L

Abstract excerpt

Multiple sclerosis (MS) is strongly associated with the HLA-Dw2 haplotype DRw15.DQw6 in Caucasoids, although the relative contributions of DR and DQ loci to disease susceptibility are unknown. The situation is further complicated by the apparent lack of an association between DR2 and MS in Orient...

Topics

Alleles
Asian People
Base Sequence
DNA
HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DR2 Antigen
Haplotypes
Hong Kong
Humans
Molecular Sequence Data
Multiple Sclerosis

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Identifiers

PMID: 1567812
DOI: 10.1111/j.1744-313x.1992.tb00043.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1567812-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Novel HLA-DR2-related haplotypes in Hong Kong Chinese implicate the DQB1*0602 allele in susceptibility to multiple sclerosis.PMID 1567812Read ↗

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