Article
Genetic susceptibility to multiple sclerosis in a Shanghai Chinese population. The role of the HLA class II genes.
Human immunology - 1 Mar 1995
Kelly M A, Zhang Y, Penny M A, Jacobs K H, Cavan D A, Mijovic C H, Chou K Y, Barnett A H, Francis D A
Abstract excerpt
The association of MS with the HLA class II loci DR and DQ was investigated in subjects of Shanghai Chinese and British Caucasian origin. Our aim was to determine whether common alleles predispose to the disease in both races. In the Caucasian population MS was significantly positively associated with the putative haplotype DRB1*1501, DQA1*0102, DQB1*0602. In contrast, HLA class II alleles were not found to...
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