Article
Evidence for a complex role of HLA class II genotypes in susceptibility to multiple sclerosis in Iceland.
Neurology - 1 Apr 1996
Haegert D G, Swift F V, Benedikz J
Abstract excerpt
We analyzed the association of HLA-DR and -DQ haplotypes and alleles with multiple sclerosis (MS) in 91 patients and 91 controls from Iceland using the relative predispositional effect method. The aim was to establish whether there is heterogeneity in HLA associations with MS, whether there are both predispositional and protective haplotypes, and whether sequence motifs also contribute to MS susceptibility. MS...
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