Article
HLA-DR and -DQ allelic sequences in multiple sclerosis patients are identical to those found in the general population.
Human immunology - 1 Nov 1991
Cowan E P, Pierce M L, McFarland H F, McFarlin D E
Abstract excerpt
The HLA-DR2/Dw2 haplotype is associated with multiple sclerosis (MS) in the North American Caucasian population. HLA-DRB, -DQA, and -DQB N-terminal domain sequences derived from amplified cDNA in a series of North American Caucasian MS patients were examined to determine if unique or rare class II alleles could be found. In addition, class II allelic sequences were analyzed from clinically discordant,...
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