Article
Analysis of HLA-DR2-associated polymorphisms by oligonucleotide hybridization in an Asian Indian population.
Human immunology - 1 Dec 1991
Mehra N K, Verduijn W, Taneja V, Drabbels J, Singh S P, Giphart M J
Abstract excerpt
Among major histocompatibility complex class II antigens, HLA-DR2 appears to have a much larger degree of polymorphism than usually recognized by routine serology or restriction fragment length polymorphisms. We have utilized oligonucleotide probes to further identify the DR2 specificity and its molecular subtypes on the basis of specific DNA sequences as they occur in a select sample from the Asian Indian...
Topics
- Alleles
- Base Sequence
- DNA
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR2 Antigen
- Haplotypes
- Humans
- India
- Leprosy, Tuberculoid
- Molecular Sequence Data