Article
Cloning of a novel gene for quinolone resistance from a transferable plasmid in Shigella flexneri 2b.
Antimicrobial agents and chemotherapy - 1 Feb 2005
Hata Mami, Suzuki Masahiro, Matsumoto Masakado, Takahashi Masao, Sato Katsuhiko, Ibe Shiro, Sakae Kenji
Abstract excerpt
A novel gene for quinolone resistance was cloned from a transferable plasmid carried by a clinical isolate of Shigella flexneri 2b that was resistant to fluoroquinolones. The plasmid conferred low-level resistance to quinolones on Escherichia coli HB101. The protein encoded by the gene showed 59% amino acid identity with Qnr.
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