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Article

Smaqnr, a new chromosome-encoded quinolone resistance determinant in Serratia marcescens

26 Nov 2009

Abstract excerpt

OBJECTIVES: A new pentapeptide repeat (PRP) protein, named SmaQnr, from the clinically relevant species Serratia marcescens, which decreased susceptibility to quinolones when expressed in Escherichia coli, is reported herein. METHODS: In silico analysis revealed the presence of a gene encoding a Qnr-like protein that shares 80% amino acid identity with QnrB1 in the S. marcescens strain Db11. Fragments carrying...

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Share to Antibiotic Resistance in Bacteria
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PMID: 19942618
DOI: 10.1093/jac/dkp424

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