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Article

Intrinsic resistance of Mycobacterium smegmatis to fluoroquinolones may be influenced by new pentapeptide protein MfpA.

Antimicrobial agents and chemotherapy - 1 Dec 2001

Montero C, Mateu G, Rodriguez R, Takiff H

Abstract excerpt

The fluoroquinolones (FQ) are used in the treatment of Mycobacterium tuberculosis, but the development of resistance could limit their effectiveness. FQ resistance (FQ(R)) is a multistep process involving alterations in the type II topoisomerases and perhaps in the regulation of efflux pumps, but several of the steps remain unidentified. Recombinant plasmid pGADIV was selected from a genomic library of wild-type...

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Identifiers

PMID: 11709313
DOI: 10.1128/AAC.45.12.3387-3392.2001
PMCID: PMC90842

Genes

SPX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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